RAF Typhoon jets have operated alongside French aircraft in a joint strike targeting an subterranean weapons facility in Syria used by the IS group, per a report from the UK's MoD.
The location, pinpointed through surveillance, was believed to be housing weapons and explosive materials, the release indicated, and was located in mountains just to the north of the ancient city of Palmyra in central Syria.
"Our aircraft utilized laser-guided Paveway IV weapons to target a number of access tunnels down to the depot... early reports are that the objective was successfully hit," the ministry announced.
There was no indication of any harm to civilians in the operation late on Saturday and each participating jet made a safe return, the ministry further stated.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as the so-called Islamic State - enforced extremist governance over parts of Syria and Iraq before its territorial defeat in 2019.
"This strike demonstrates British leadership, and commitment to work closely with our partners, to eliminate any revival of Daesh and their dangerous and violent ideologies in the Middle East," the British Defence Secretary the minister remarked.
UK warplanes have performed surveillance missions over Syrian airspace to "prevent any attempted resurgence" of IS following its defeat at the climactic battle in Baghuz in 2019, the ministry said.
"I must thank the personnel of the UK armed forces involved in this strike for their professionalism and their valour," the Defence Secretary said. "They were part of numerous British personnel deployed over the festive period. This action, to take out militants who threaten our safety, highlights how UK forces are prepared to act, all year round, keeping Britain secure domestically and strong abroad."
Last December, the US military carried out what it called a "major assault" targeting IS targets in the country, subsequent to an attack resulted in the deaths of two US servicemembers and a civilian interpreter in the Palmyra area.
The United Nations says Islamic State still boasts roughly 5-7 thousand combatants in Iraq and Syria.